CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family protein tyrosine phosphatase type IVA 1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q93096
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q93096
TP4A1_HUMAN
Homo sapiens
Protein tyrosine phosphatase type IVA 1

PDB Structure

PDB 1XM2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms
Jeong, D.G., Kim, S.J., Kim, J.H., Son, J.H., Park, M.R., Lim, S.M., Yoon, T.S., Ryu, S.E.
J.Mol.Biol.