CATH Classification

Domain Context

CATH Clusters

Superfamily Helix hairpin bin
Functional Family DNA polymerase

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P03680
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
3.1.11.-
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt P03680

UniProtKB Entries (1)

P03680
DPOL_BPPH2
Bacillus virus phi29
DNA polymerase

PDB Structure

PDB 1XHZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29
Kamtekar, S., Berman, A.J., Wang, J., Lazaro, J.M., de Vega, M., Blanco, L., Salas, M., Steitz, T.A.
Mol.Cell