CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1970
Functional Family 3-dehydroquinate synthase

Enzyme Information

4.2.3.4
3-dehydroquinate synthase.
based on mapping to UniProt Q6GGU4
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate.
-!- The hydrogen atoms on C-7 of the substrate are retained on C-2 of the products. -!- Formerly EC 4.6.1.3.

UniProtKB Entries (1)

Q6GGU4
AROB_STAAR
Staphylococcus aureus subsp. aureus MRSA252
3-dehydroquinate synthase

PDB Structure

PDB 1XAH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Comparison of ligand induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases.
Nichols, C.E., Ren, J., Leslie, K., Dhaliwal, B., Lockyer, M., Charles, I., Hawkins, A.R., Stammers, D.K.
J.Mol.Biol.