CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
6 | Special |
|
6.20 | Other non-globular |
|
6.20.440 | Translocated Intimin Receptor; Chain T |
|
6.20.440.10 |
Domain Context
CATH Clusters
| Superfamily | 6.20.440.10 |
| Functional Family |
Enzyme Information
| 1.4.4.2 |
Glycine dehydrogenase (aminomethyl-transferring).
based on mapping to UniProt Q5SKW7
Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L- lysine + CO(2).
-!- A component of the glycine cleavage system, which is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein. -!- Previously known as glycine synthase.
|
UniProtKB Entries (1)
| Q5SKW8 |
Q5SKW8_THET8
Thermus thermophilus HB8
Probable glycine dehydrogenase (decarboxylating) subunit 1
|
PDB Structure
| PDB | 1WYV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia
Embo J.
|
