CATH Classification

Domain Context

CATH Clusters

Superfamily N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Functional Family Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Enzyme Information

1.1.1.8
Glycerol-3-phosphate dehydrogenase (NAD(+)).
based on mapping to UniProt P21695
sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.
-!- Also acts on propane-1,2-diol phosphate and glycerone sulfate (but with a much lower affinity).

UniProtKB Entries (1)

P21695
GPDA_HUMAN
Homo sapiens
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

PDB Structure

PDB 1WPQ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1)
Ou, X., Ji, C., Han, X., Zhao, X., Li, X., Mao, Y., Wong, L.L., Bartlam, M., Rao, Z.
J.Mol.Biol.