CATH Classification

Domain Context

CATH Clusters

Superfamily Arylamine N-acetyltransferase
Functional Family

Enzyme Information

2.3.1.5
Arylamine N-acetyltransferase.
based on mapping to UniProt O86309
Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
-!- Wide specificity for aromatic amines, including serotonin; also catalyzes acetyl-transfer between arylamines without CoA.

UniProtKB Entries (1)

O86309
NAT_MYCSM
Mycolicibacterium smegmatis
Arylamine N-acetyltransferase

PDB Structure

PDB 1W5R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Investigation of the Catalytic Triad of Arylamine N-Acetyltransferases: Essential Residues Required for Acetyl Transfer to Arylamines.
Sandy, J., Mushtaq, A., Holton, S.J., Schartau, P., Noble, M.E.M., Sim, E.
Biochem.J.