CATH Classification

Domain Context

CATH Clusters

Superfamily SGNH hydrolase
Functional Family Platelet-activating factor acetylhydrolase IB subunit beta

Enzyme Information

3.1.1.47
1-alkyl-2-acetylglycerophosphocholine esterase.
based on mapping to UniProt P68402
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl- sn-glycero-3-phosphocholine + acetate.

UniProtKB Entries (2)

P63005
LIS1_MOUSE
Mus musculus
Platelet-activating factor acetylhydrolase IB subunit alpha
P68402
PA1B2_HUMAN
Homo sapiens
Platelet-activating factor acetylhydrolase IB subunit beta

PDB Structure

PDB 1VYH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Coupling Paf Signaling to Dynein Regulation: Structure of Lis1 in Complex with Paf-Acetylhydrolase.
Tarricone, C., Perrina, F., Monzani, S., Massimiliano, L., Kim, M.H., Derewenda, Z.S., Knapp, S., Tsai, L.-H., Musacchio, A.
Neuron