1 keywords

CATH Domain 1vq3C00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1280 Mth169; Chain: A ,
Homologous Superfamily 3.30.1280.10 Phosphoribosylformylglycinamidine synthase subunit PurS

Domain Context

CATH Clusters

Superfamily Phosphoribosylformylglycinamidine synthase subunit PurS
Functional Family

Enzyme Information

6.3.5.3
Phosphoribosylformylglycinamidine synthase.
based on mapping to UniProt Q9X0X1
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.

UniProtKB Entries (1)

Q9X0X1
PURS_THEMA
Thermotoga maritima MSB8
Phosphoribosylformylglycinamidine synthase subunit PurS

PDB Structure

PDB 1VQ3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution.
Mathews, I.I., Krishna, S.S., Schwarzenbacher, R., McMullan, D., Jaroszewski, L., Miller, M.D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H.L., Canaves, J.M., Carlton, D., Chiu, H.J., Clayton, T., DiDonato, M., Duan, L., Elsliger, M.A., Grzechnik, S.K., Hale, J., Hampton, E., Haugen, J., Jin, K.K., Klock, H.E., Koesema, E., Kovarik, J.S., Kreusch, A., Kuhn, P., Levin, I., Morse, A.T., Nigoghossian, E., Okach, L., Oommachen, S., Paulsen, J., Quijano, K., Reyes, R., Rife, C.L., Spraggon, G., Stevens, R.C., van den Bedem, H., White, A., Wolf, G., Xu, Q., Hodgson, K.O., Wooley, J., Deacon, A.M., Godzik, A., Lesley, S.A., Wilson, I.A.
Proteins