CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt Q9WZ26
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

Q9WZ26
LEU3_THEMA
Thermotoga maritima MSB8
3-isopropylmalate dehydrogenase

PDB Structure

PDB 1VLC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of 3-isopropylmalate dehydrogenase (TM0556) from Thermotoga maritima at 1.90 A resolution
Joint Center for Structural Genomics (JCSG)
To be published