CATH Classification

Domain Context

CATH Clusters

Superfamily Tyrosyl-Transfer RNA Synthetase
Functional Family Tyrosine--tRNA ligase

Enzyme Information

6.1.1.1
Tyrosine--tRNA ligase.
based on mapping to UniProt P0AGJ9
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).

UniProtKB Entries (1)

P0AGJ9
SYY_ECOLI
Escherichia coli K-12
Tyrosine--tRNA ligase

PDB Structure

PDB 1VBM
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase.
Kobayashi, T., Takimura, T., Sekine, R., Kelly, V.P., Vincent, K., Kamata, K., Sakamoto, K., Nishimura, S., Yokoyama, S.
J.Mol.Biol.