CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.30.20
Functional Family Tail spike protein

Enzyme Information

3.2.1.129
Endo-alpha-sialidase.
based on mapping to UniProt Q04830
Endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.
-!- Although the name endo-N-acetylneuraminidase has also been used for this enzyme, this is misleading since its activity is not restricted to acetyl-substituted substrates. -!- An exo-alpha-sialidase activity is listed as EC 3.2.1.18. -!- See also 4.2.2.15.

UniProtKB Entries (1)

Q04830
FIBER_BPK1F
Enterobacteria phage K1F
Tail spike protein

PDB Structure

PDB 1V0E
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F
Stummeyer, K., Dickmanns, A., Muehlenhoff, M., Gerardy-Schahn, R., Ficner, R.
Nat.Struct.Mol.Biol.