CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P80040
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P80040
MDH_CHLAA
Chloroflexus aurantiacus J-10-fl
Malate dehydrogenase

PDB Structure

PDB 1UXI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface.
Bjork, A., Dalhus, B., Mantzilas, D., Sirevag, R., Eijsink, V.G.H.
J.Mol.Biol.