CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Probable uracil phosphoribosyltransferase

Enzyme Information

2.4.2.9
Uracil phosphoribosyltransferase.
based on mapping to UniProt Q26998
UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate.

UniProtKB Entries (1)

Q26998
UPP_TOXGO
Toxoplasma gondii
Uracil phosphoribosyltransferase

PDB Structure

PDB 1UPU
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
Schumacher, M.A., Carter, D., Scott, D.M., Roos, D.S., Ullman, B., Brennan, R.G.
EMBO J.