CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C
Functional Family Thymidine phosphorylase

Enzyme Information

2.4.2.4
Thymidine phosphorylase.
based on mapping to UniProt P19971
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
-!- In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

P19971
TYPH_HUMAN
Homo sapiens
Thymidine phosphorylase

PDB Structure

PDB 1UOU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Thymidine Phosphorylase in Complex with a Small Molecule Inhibitor
Norman, R.A., Barry, S.T., Bate, M., Breed, J., Colls, J.G., Ernill, R.J., Luke, R.W.A., Minshull, C.A., Mcalister, M.S.B., Mccall, E.J., Mcmicken, H.H.J., Paterson, D.S., Timms, D., Tucker, J.A., Pauptit, R.A.
Structure