CATH Classification

Domain Context

CATH Clusters

Superfamily Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Functional Family

Enzyme Information

6.1.1.5
Isoleucine--tRNA ligase.
based on mapping to UniProt P56690
ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).

UniProtKB Entries (1)

P56690
SYI_THET8
Thermus thermophilus HB8
Isoleucine--tRNA ligase

PDB Structure

PDB 1UE0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine.
Fukunaga, R., Fukai, S., Ishitani, R., Nureki, O., Yokoyama, S.
J.Biol.Chem.