CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P15531
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

P15531
NDKA_HUMAN
Homo sapiens
Nucleoside diphosphate kinase A

PDB Structure

PDB 1UCN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Nucleotide Binding to Nucleoside Diphosphate Kinases: X-ray Structure of Human NDPK-A in Complex with ADP and Comparison to Protein Kinases
Chen, Y., Gallois-Montbrun, S., Schneider, B., Veron, M., Morera, S., Deville-Bonne, D., Janin, J.
J.Mol.Biol.