CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.20 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.20 |
| Functional Family |
Enzyme Information
| 6.3.2.43 |
[Amino group carrier protein]--L-2-aminoadipate ligase.
based on mapping to UniProt Q5SH23
ATP + [amino group carrier protein]-C-terminal-L-glutamate + L-2- aminoadipate = ADP + phosphate + [amino group carrier protein]-C- terminal-gamma-(L-2-aminoadip-2-yl)-L-glutamate.
-!- The enzymes from the thermophilic bacterium Thermus thermophilus and the thermophilic archaea Sulfolobus acidocaldarius and Sulfolobus tokodaii protect the amino group of L-2-aminoadipate by conjugation to the carrier protein LysW. -!- This reaction is part of the lysine biosynthesis pathway in these organisms. -!- Formerly EC 6.3.2.n4.
|
UniProtKB Entries (1)
| Q5SH23 |
LYSX_THET8
Thermus thermophilus HB8
Alpha-aminoadipate--LysW ligase LysX
|
PDB Structure
| PDB | 1UC8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8
J.Mol.Biol.
|