CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome-c3 Hydrogenase, chain B
Functional Family Hydrogenase 2 large subunit

Enzyme Information

1.12.2.1
Cytochrome-c3 hydrogenase.
based on mapping to UniProt P21852
H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.
-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P21853
PHNS_DESVM
Desulfovibrio vulgaris str. 'Miyazaki F'
Periplasmic [NiFe] hydrogenase small subunit

PDB Structure

PDB 1UBL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Studies of the Carbon Monoxide Complex of [NiFe]hydrogenase from Desulfovibrio vulgaris Miyazaki F: Suggestion for the Initial Activation Site for Dihydrogen
Ogata, H., Mizoguchi, Y., Mizuno, N., Miki, K., Adachi, S., Yasuoka, N., Yagi, T., Yamauchi, O., Hirota, S., Higuchi, Y.
J.Am.Chem.Soc.