CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P08515
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P08515
GST26_SCHJA
Schistosoma japonicum
Glutathione S-transferase class-mu 26 kDa isozyme

PDB Structure

PDB 1U87
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystallographic and Thermodynamic Analysis of the Binding of S-Octylglutathione to the Tyr 7 to Phe Mutant of Glutathione S-Transferase from Schistosoma japonicum(,)
Andujar-Sanchez, M., Smith, A.W., Clemente-Jimenez, J.M., Rodriguez-Vico, F., Las Heras-Vazquez, F.J., Jara-Perez, V., Camara-Artigas, A.
Biochemistry