CATH Classification

Domain Context

CATH Clusters

Superfamily Diaminopimelate Epimerase; Chain A, domain 1
Functional Family

Enzyme Information

5.3.3.17
Trans-2,3-dihydro-3-hydroxyanthranilate isomerase.
based on mapping to UniProt Q51792
(5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate = (1R,6S)-6- amino-5-oxocyclohex-2-ene-1-carboxylate.
-!- The enzyme is involved in phenazine biosynthesis. -!- The enzyme is involved in phenazine biosynthesis. -!- The product probably spontaneously dimerises to 1,4,5a,6,9,10a- hexahydrophenazine-1,6-dicarboxylate.

UniProtKB Entries (1)

Q51792
PHZF_PSEFL
Pseudomonas fluorescens
Trans-2,3-dihydro-3-hydroxyanthranilate isomerase

PDB Structure

PDB 1U1V
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens.
Blankenfeldt, W., Kuzin, A.P., Skarina, T., Korniyenko, Y., Tong, L., Bayer, P., Janning, P., Thomashow, L.S., Mavrodi, D.V.
Proc.Natl.Acad.Sci.USA