CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family Uridine phosphorylase

Enzyme Information

2.4.2.3
Uridine phosphorylase.
based on mapping to UniProt P12758
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
-!- The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage. -!- The mammalian enzyme also accepts 2'-deoxyuridine. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

P12758
UDP_ECOLI
Escherichia coli K-12
Uridine phosphorylase

PDB Structure

PDB 1U1D
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Bu, W., Settembre, E.C., el Kouni, M.H., Ealick, S.E.
Acta Crystallogr.,Sect.D