CATH Classification

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family

Enzyme Information

3.4.23.34
Cathepsin E.
based on mapping to UniProt P14091
Similar to cathepsin D, but slightly broader specificity.
-!- Found in stomach, spleen, erythrocyte membrane; not lysosomal. -!- Pro-cathepsin E is an 86 kDa disulfide-linked dimer; activation or reduction produces monomers. -!- Belongs to peptidase family A1.

UniProtKB Entries (1)

P14091
CATE_HUMAN
Homo sapiens
Cathepsin E

PDB Structure

PDB 1TZS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of an activation intermediate of cathepsin e
Ostermann, N., Gerhartz, B., Worpenberg, S., Trappe, J., Eder, J.
J.Mol.Biol.