CATH Classification

Domain Context

CATH Clusters

Superfamily Tyrosyl-Transfer RNA Synthetase
Functional Family Tyrosine--tRNA ligase

Enzyme Information

6.1.1.1
Tyrosine--tRNA ligase.
based on mapping to UniProt P00952
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).

UniProtKB Entries (1)

P00952
SYY_GEOSE
Geobacillus stearothermophilus
Tyrosine--tRNA ligase

PDB Structure

PDB 1TYC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis of a Series of Mutants of Tyrosyl-tRNA Synthetase: Enhancement of Catalysis by Hydrophobic Interactions
Brown, K.A., De Meester, P., Fersht II, A.R., Blow, D.M.
To be Published