CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.590.20
Functional Family Putative glutamate--cysteine ligase 2

Enzyme Information

6.3.2.2
Glutamate--cysteine ligase.
based on mapping to UniProt Q8ZR41
ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L- cysteine.
-!- Can use L-aminohexanoate in place of glutamate.

UniProtKB Entries (1)

Q8ZR41
GCS2_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Putative glutamate--cysteine ligase 2

PDB Structure

PDB 1TT4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium
Miller, D.J., Shuvalova, L., Anderson, W.F., Midwest Center for Structural Genomics (MCSG)
To be Published