CATH Classification

Domain Context

CATH Clusters

Superfamily Hexapeptide repeat proteins
Functional Family

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P40881
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P40881
CAH_METTE
Methanosarcina thermophila
Carbonic anhydrase

PDB Structure

PDB 1THJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila.
Kisker, C., Schindelin, H., Alber, B.E., Ferry, J.G., Rees, D.C.
EMBO J.