CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Polymerase, chain B, domain 1
Functional Family DNA polymerase

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P56689
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P56689
DPOL_THEGO
Thermococcus gorgonarius
DNA polymerase

PDB Structure

PDB 1TGO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius.
Hopfner, K.P., Eichinger, A., Engh, R.A., Laue, F., Ankenbauer, W., Huber, R., Angerer, B.
Proc.Natl.Acad.Sci.USA