CATH Classification

Domain Context

CATH Clusters

Superfamily 1.50.10.10
Functional Family Endoglucanase

Enzyme Information

3.2.1.4
Cellulase.
based on mapping to UniProt P26221
Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
-!- Will also hydrolyze 1,4-linkages in beta-D-glucans also containing 1,3-linkages.

UniProtKB Entries (1)

P26221
GUN4_THEFU
Thermobifida fusca
Endoglucanase E-4

PDB Structure

PDB 1TF4
External Links
Method X-RAY DIFFRACTION
Organism Streptomyces
Primary Citation
Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca.
Sakon, J., Irwin, D., Wilson, D.B., Karplus, P.A.
Nat.Struct.Biol.