CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1600 | SIR2/SIRT2 'Small Domain' |
|
3.30.1600.10 | SIR2/SIRT2 'Small Domain' |
Domain Context
CATH Clusters
| Superfamily | SIR2/SIRT2 'Small Domain' |
| Functional Family | NAD-dependent deacetylase sirtuin-3, mitochondrial |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt P53686
|
UniProtKB Entries (1)
| P53686 |
HST2_YEAST
Saccharomyces cerevisiae S288C
NAD-dependent protein deacetylase HST2
|
PDB Structure
| PDB | 1SZC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Proc.Natl.Acad.Sci.Usa
|