CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Structural polyprotein

Enzyme Information

3.4.21.90
Togavirin.
based on mapping to UniProt P03316
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
-!- Once released, the core protein does not retain catalytic activity. -!- Belongs to peptidase family S3.

UniProtKB Entries (1)

P03316
POLS_SINDV
Sindbis virus
Structural polyprotein

PDB Structure

PDB 1SVP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly.
Lee, S., Owen, K.E., Choi, H.K., Lee, H., Lu, G., Wengler, G., Brown, D.T., Rossmann, M.G., Kuhn, R.J.
Structure