CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P59071
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P59071
PA2B8_DABRR
Daboia russelii
Basic phospholipase A2 VRV-PL-VIIIa

PDB Structure

PDB 1SKG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser
Ethayathulla, A.S., Singh, N., Sharma, S., Makker, J., Dey, S., Perbandt, M., Betzel, C., Singh, T.P.
To be Published