CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family Beta-galactoside-specific lectin 1

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt P06750
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

P06750
AGGL_RICCO
Ricinus communis
Agglutinin

PDB Structure

PDB 1RZO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-function investigation complex of Agglutinin from Ricinus communis with galactoaza
Gabdoulkhakov, A.G., Savochkina, Y., Konareva, N., Krauspenhaar, R., Stoeva, S., Nikonov, S.V., Voelter, W., Betzel, C., Mikhailov, A.M.
To be Published