CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Cationic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00760
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P00760
TRY1_BOVIN
Bos taurus
Cationic trypsin

PDB Structure

PDB 1RXP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors
Sutton, J.C., Bolton, S.A., Davis, M.E., Hartl, K.S., Jacobson, B., Mathur, A., Ogletree, M.L., Slusarchyk, W.A., Zahler, R., Seiler, S.M., Bisacchi, G.S.
Bioorg.Med.Chem.Lett.