CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.300.10
Functional Family S-adenosylmethionine synthase

Enzyme Information

2.5.1.6
Methionine adenosyltransferase.
based on mapping to UniProt P0A817
ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L- methionine.
-!- Formerly EC 2.4.2.13.

UniProtKB Entries (1)

P0A817
METK_ECOLI
Escherichia coli K-12
S-adenosylmethionine synthase

PDB Structure

PDB 1RG9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of s-adenosylmethionine synthesis from ATP and MET.
Komoto, J., Yamada, T., Takata, Y., Markham, G.D., Takusagawa, F.
Biochemistry