CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt P23381
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

P23381
SYWC_HUMAN
Homo sapiens
Tryptophan--tRNA ligase, cytoplasmic

PDB Structure

PDB 1R6T
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Yang, X.-L., Otero, F.J., Skene, R.J., McRee, D.E., Schimmel, P., Ribas De Pouplana, L.
Proc.Natl.Acad.Sci.USA