1 keywords

CATH Domain 1r6gA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Thyroid hormone receptor beta 2

Enzyme Information

UniProtKB Entries (1)

P10828
THB_HUMAN
Homo sapiens
Thyroid hormone receptor beta

PDB Structure

PDB 1R6G
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta.
Hangeland, J.J., Doweyko, A.M., Dejneka, T., Friends, T.J., Devasthale, P., Mellstrom, K., Sandberg, J., Grynfarb, M., Sack, J.S., Einspahr, H., Farnegardh, M., Husman, B., Ljunggren, J., Koehler, K., Sheppard, C., Malm, J., Ryono, D.E.
Bioorg.Med.Chem.Lett.