CATH Classification

Domain Context

CATH Clusters

Superfamily Chorismate synthase AroC
Functional Family

Enzyme Information

4.2.3.5
Chorismate synthase.
based on mapping to UniProt P28777
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
-!- The reaction goes via a radical mechanism that involves reduced FMN and its semiquinone (FMNH.). -!- Shikimate is numbered so that the double-bond is between C-1 and C-2, but some earlier papers numbered the ring in the reverse direction. -!- Formerly EC 4.6.1.4.

UniProtKB Entries (1)

P28777
AROC_YEAST
Saccharomyces cerevisiae S288C
Chorismate synthase

PDB Structure

PDB 1R52
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae
Quevillon-Cheruel, S., Leulliot, N., Meyer, P., Graille, M., Bremang, M., Blondeau, K., Sorel, I., Poupon, A., Janin, J., van Tilbeurgh, H.
J.Biol.Chem.