CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt O68720
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

O68720
O68720_YERPE
Yersinia pestis
Targeted effector protein

PDB Structure

PDB 1QZ0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
High-Resolution Structure of the Yersinia pestis Protein Tyrosine Phosphatase YopH in Complex with a Phosphotyrosyl Mimetic-Containing Hexapeptide
Phan, J., Lee, K., Cherry, S., Tropea, J.E., Burke Jr, T.R., Waugh, D.S.
Biochemistry