CATH Classification

Domain Context

CATH Clusters

Superfamily Chorismate synthase AroC
Functional Family Chorismate synthase

Enzyme Information

4.2.3.5
Chorismate synthase.
based on mapping to UniProt P0A2Y6
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
-!- The reaction goes via a radical mechanism that involves reduced FMN and its semiquinone (FMNH.). -!- Shikimate is numbered so that the double-bond is between C-1 and C-2, but some earlier papers numbered the ring in the reverse direction. -!- Formerly EC 4.6.1.4.

UniProtKB Entries (1)

P0A2Y6
AROC_STRPN
Streptococcus pneumoniae TIGR4
Chorismate synthase

PDB Structure

PDB 1QXO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of chorismate synthase reveals a novel flavin binding site fundamental to a unique chemical reaction
Maclean, J., Ali, S.
Structure