CATH Classification

Domain Context

CATH Clusters

Superfamily Bacterial muramidases
Functional Family Soluble lytic murein transglycosylase

Enzyme Information

4.2.2.n1
Peptidoglycan lytic exotransglycosylase.
based on mapping to UniProt P0AGC3
Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.

UniProtKB Entries (1)

P0AGC3
SLT_ECOLI
Escherichia coli K-12
Soluble lytic murein transglycosylase

PDB Structure

PDB 1QTE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
High resolution crystal structures of the Escherichia coli lytic transglycosylase Slt70 and its complex with a peptidoglycan fragment.
van Asselt, E.J., Thunnissen, A.M., Dijkstra, B.W.
J.Mol.Biol.