CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.7
Plasmin.
based on mapping to UniProt P00747
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
-!- Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.14.

UniProtKB Entries (1)

P00747
PLMN_HUMAN
Homo sapiens
Plasminogen

PDB Structure

PDB 1QRZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the proenzyme domain of plasminogen.
Peisach, E., Wang, J., de los Santos, T., Reich, E., Ringe, D.
Biochemistry