CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | Astacin |
Enzyme Information
| 3.4.24.21 |
Astacin.
based on mapping to UniProt P07584
Hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'.
-!- A digestive endopeptidase from the cardia of the crayfish Astacus fluviatilis. -!- Belongs to peptidase family M12A. -!- Formerly EC 3.4.99.6.
|
UniProtKB Entries (1)
| P07584 |
ASTA_ASTAS
Astacus astacus
Astacin
|
PDB Structure
| PDB | 1QJJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of Astacin with a Transition-State Analogue Inhibitor
Nat.Struct.Biol.
|