CATH Classification

Domain Context

CATH Clusters

Superfamily Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
Functional Family

Enzyme Information

1.3.5.4
Fumarate reductase (quinol).
based on mapping to UniProt Q07WU7
Succinate + a quinone = fumarate + a quinol.
-!- The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain. -!- The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, to which it is closely related.

UniProtKB Entries (1)

Q07WU7
FRDA_SHEFN
Shewanella frigidimarina NCIMB 400
Fumarate reductase flavoprotein subunit

PDB Structure

PDB 1QJD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Mechanistic Mapping of a Unique Fumarate Reductase
Taylor, P., Pealing, S.L., Reid, G.A., Chapman, S.K., Walkinshaw, M.D.
Nat.Struct.Biol.