CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family Hydroxyacylglutathione hydrolase, mitochondrial

Enzyme Information

3.1.2.6
Hydroxyacylglutathione hydrolase.
based on mapping to UniProt Q16775
S-(2-hydroxyacyl)glutathione + H(2)O = glutathione + a 2-hydroxy carboxylate.
-!- Also hydrolyzes S-acetoacetylglutathione, more slowly. -!- Formerly EC 3.1.2.8.

UniProtKB Entries (1)

Q16775
GLO2_HUMAN
Homo sapiens
Hydroxyacylglutathione hydrolase, mitochondrial

PDB Structure

PDB 1QH3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Structure Fold.Des.