CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module
Functional Family Ferredoxin--NADP reductase, chloroplastic

Enzyme Information

1.18.1.2
Ferredoxin--NADP(+) reductase.
based on mapping to UniProt P10933
2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH.
-!- In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin. -!- Formerly EC 1.6.7.1 and EC 1.6.99.4.

UniProtKB Entries (1)

P10933
FENR1_PEA
Pisum sativum
Ferredoxin--NADP reductase, leaf isozyme, chloroplastic

PDB Structure

PDB 1QGA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A productive NADP+ binding mode of ferredoxin-NADP+ reductase revealed by protein engineering and crystallographic studies.
Deng, Z., Aliverti, A., Zanetti, G., Arakaki, A.K., Ottado, J., Orellano, E.G., Calcaterra, N.B., Ceccarelli, E.A., Carrillo, N., Karplus, P.A.
Nat.Struct.Biol.