CATH Classification

Domain Context

CATH Clusters

Superfamily RutC-like
Functional Family

Enzyme Information

3.1.-.-
Acting on ester bonds.
based on mapping to UniProt P52759
3.5.99.10
2-iminobutanoate/2-iminopropanoate deaminase.
based on mapping to UniProt P52759
(1) 2-iminobutanoate + H(2)O = 2-oxobutanoate + NH(3). (2) 2-iminopropanoate + H(2)O = pyruvate + NH(3).
-!- This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. -!- The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates.

UniProtKB Entries (1)

P52759
RIDA_RAT
Rattus norvegicus
2-iminobutanoate/2-iminopropanoate deaminase

PDB Structure

PDB 1QAH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Perchloric Acid Soluble Protein-a Translational Inhibitor
Djinovic Carugo, K., Oka, T.
To be Published