CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.2250
Functional Family DNA polymerase

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P21189
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P21189
DPO2_ECOLI
Escherichia coli K-12
DNA polymerase II

PDB Structure

PDB 1Q8I
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Escherichia Coli DNA Polymerase II
Brunzelle, J.S., Muchmore, C.R.A., Mashhoon, N., Blair-Johnson, M., Shuvalova, L., Goodman, M.F., Anderson, W.F.
To be Published