CATH Classification

Domain Context

CATH Clusters

Superfamily Enolpyruvate transferase domain
Functional Family UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Enzyme Information

2.5.1.7
UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
based on mapping to UniProt P33038
Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP- N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine.

UniProtKB Entries (1)

P33038
MURA_ENTCC
Enterobacter cloacae subsp. cloacae ATCC 13047
UDP-N-acetylglucosamine 1-carboxyvinyltransferase

PDB Structure

PDB 1Q3G
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States.
Eschenburg, S., Kabsch, W., Healy, M.L., Schonbrunn, E.
J.Biol.Chem.