CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.140.230
Functional Family

Enzyme Information

5.4.99.23
23S rRNA pseudouridine(1911/1915/1917) synthase.
based on mapping to UniProt P33643
23S rRNA uridine(1911)/uridine(1915)/uridine(1917) = 23S rRNA pseudouridine(1911)/pseudouridine(1915)/pseudouridine(1917).
-!- Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines. -!- These nucleotides are located in the functionally important helix- loop 69 of 23S rRNA.

UniProtKB Entries (1)

P33643
RLUD_ECOLI
Escherichia coli K-12
Ribosomal large subunit pseudouridine synthase D

PDB Structure

PDB 1PRZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the RluD pseudouridine Synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli
Sivaraman, J., Iannuzzi, P., Cygler, M., Matte, A.
J.Mol.Biol.