CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.2350 | Pseudouridine synthase |
|
3.30.2350.10 | Pseudouridine synthase |
Domain Context
CATH Clusters
| Superfamily | Pseudouridine synthase |
| Functional Family |
Enzyme Information
| 5.4.99.23 |
23S rRNA pseudouridine(1911/1915/1917) synthase.
based on mapping to UniProt P33643
23S rRNA uridine(1911)/uridine(1915)/uridine(1917) = 23S rRNA pseudouridine(1911)/pseudouridine(1915)/pseudouridine(1917).
-!- Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines. -!- These nucleotides are located in the functionally important helix- loop 69 of 23S rRNA.
|
UniProtKB Entries (1)
| P33643 |
RLUD_ECOLI
Escherichia coli K-12
Ribosomal large subunit pseudouridine synthase D
|
PDB Structure
| PDB | 1PRZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of the RluD pseudouridine Synthase catalytic module, an
enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli
J.Mol.Biol.
|