CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family Purine nucleoside phosphorylase DeoD-type

Enzyme Information

2.4.2.1
Purine-nucleoside phosphorylase.
based on mapping to UniProt P0ABP9
(1) Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. (2) Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.
-!- Specificity not completely determined. -!- Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5.

UniProtKB Entries (1)

P0ABP9
DEOD_ECO57
Escherichia coli O157:H7
Purine nucleoside phosphorylase DeoD-type

PDB Structure

PDB 1PR4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
J.Biol.Chem.